Why We Get Fat: Seeking Clues in Our Cells - Overcoming Obesity - TIME

Losing weight can seem like an unwinnable war. You know you need to eat less and exercise more, but that's nearly impossible when everything in your life — from job stress to family crises to the temptation of fast and fatty foods — encourages you to do the opposite. A healthy diet and regular exercise are certainly the best weapons against weight gain, but the fact is that sometimes they aren't enough. And that's where science may someday be able to help.